“Polyethylenimine grafted-chitosan based Gambogic acid copolymers for targeting cancer cells overexpressing transferrin acid copolymers for targeting cancer cells overexpressing transferrin receptors”, Carbohydrate Polymer, Sung-Cheol Park, Hun Heo, Mi-Kyeong Jang, 277, (2022) (IF:9.381, JCR 상위 3.97%)
“Imaging and Targeted Antibacterial Therapy Using Chimeric Antimicrobial Peptide Micelles”, ACS Applied Materials & Interfaces, Sung-Cheol Park, Chang-Gun Ko, Hye-Jin Han, Dong-Won Lee, Mi-Kyeong Jang, 12, (2020) (IF:8.758)
“Improved cell selectivity of pseudin-2 via substitution in the leucine-zipper motif: In vitro and in vivo antifungal activity”, Antibiotics, Sung-Cheol Park, Hye-Bin Kim, Jin-Young Kim, Hyun-Seok Kim, Gwang-Woo Cheong, Jung-Ro Lee, Mi-Kyeong Jang 9(12), (2020) (IF:3.893)
“Antifungal Effect of A Chimeric Peptide Hn-Mc against Pathogenic Fungal Strains”, Antibiotics(Basel), Sung-Cheol Park, Jin-Young Kim, Kwang-bok No, Hye-Bin Kim, Jung-Ro Lee, Mi-Kyeong Jang et. al., 9(8) (2020) (IF:3.893)
“Functional Characterization of a Rice Thioredoxin Protein OsTrxm and Its Cysteine Mutant Variant with Antifungal Activity”, Sung-Cheol Park, Jin-Young Kim, Jung-Ro Lee, Mi-Kyeong Jang et. al., Antioxidants, 8(12) (2019) (IF:4.52)
“Functional Mechanisms Underlying the Antimicrobial Activity of the Oryza sativa Trx-like Protein”, International Journal of Molecular Science, Sung-Cheol Park, Jin-Young Kim, Jung-Ro Lee, Mi-Kyeong Jang et. al., 20(6) (2019) (IF:3.687)
“Molecular mechanism of Arabidopsis thaliana profilins as antifungal proteins”, Biochimica et Biophysica Acta (BBA) - General Subjects, Sung-Cheol Park, Jin-Young Kim, Jung-Ro Lee, Mi-Kyeong Jang et. al., 1862(12), (2018) (IF:3.679)
“Hydrophilic Linear Peptide with Histidine and Lysine Residues as a Key Factor Affecting Antifungal Activity”, International Journal of Molecular Science, Sung-cheol Park, Eun-Ji Kim, Jung-Ro Lee, Mi-Kyeong Jang et. al. 19(12), (2018) (IF:3.687)
“One-step synthesis of gene carrier via gamma irradiation and its application in tumor gene therapy”, International Journal of Nanomedicine, Sung In Jeong, Seong-cheol Park, Sun-Jeong Park, Eum-Ji Kim, Hum Heo, Jong-Seok Park, Hui-Jeong Gwon, Youn-Mook Lim, Mi-Kyeong Jang, 13 (2018)(IF:4.3)
“Targeted gene delivery of polyethyleneimine-grafted chitosan with RGD dendrimer peptide in αvβ3 integrin-overexpressing tumor cells” Carbohydrate Polymers, Young-Min Kim, Seong-Cheol Park, Mi-Kyeong Jang, 174 (2017)(IF:4.811)
“Antifungal Effect of Arabidopsis SGT1 Proteins via Mitochondrial Reactive Oxygen Species”, Journal of agricultural and food chemistry, Seong-Cheol Park, Mi-Seon Jeong, Eun-Ji Kim, Jin-Hyo Kim, Young-Hun Ji, Mi-Kyeong Jang, 65(38) (2017) (IF:3.154)
“Targeted doxorubicin delivery based on avidin-biotin technology in cervical tumor cells”, Macromolecular Research, Seong-Cheol Park, Young-Min Kim, Nam-Hong Kim, Eun-Ji Kim, Yong-Hun Park, Jung-Ro Lee, Mi-Kyeong Jang, 25(9) (2017) (IF:1.405)
“Targeting and synergistic action of an antifungal peptide in an antibiotic drug-delivery system”, Journal of Controlled Release, Young-Min Kim, Sung-Cheol Park, Jong-Kuk Lee, Nam-Hong Kim, Eun-Ji Kim, Hun-Heo, Min-Young Lee, Jung-Ro Lee, Mi-Kyeong Jang, 256, (2017)(IF:7.441)
“Functional characterization of the Arabidopsis universal stress protein AtUSP with an antifungal activity”, Biochemical and Biophysical Research Communications, Seong-Cheol Park, Young-Jun Jeong, Yong-Jae Lee, Il-Lyong Kim, Min-A Seol, Eun-Ji Kim, Jung-Ro Lee, Mi-Kyeong Jang, 486(4) (2017)(IF : 2.371)
항조류 활성을 가지는 키메라 펩타이드 및 이를 유효성분으로 함유하는 적조 방제용 조성물등록번호 : 10-1746667-0000, 등록일자 : 2017년 06.07
항균 활성을 나타내는 이소소르비드 유도체 및 이를 유효성분으로 포함하는 항균용 조성물등록번호 : 10-1959994, 등록일자 : 2019-03-13
항염증 활성을 나타내는 펩타이드 및 이를 유효성분으로 포함하는 항염증용 조성물등록번호 : 10-2032945, 등록일자 : 2019-10-10
약물내성균과 생물막에 향균 활성을 가지는 알파-헬리컬 펩타이드 및 이를 포함하는 항균용 조성물등록번호 : 10-1983679, 등록일자 : 2019-05-23
암포테리신 B를 포함하는 약물 전달용 나노입자 및 이를 포함하는 항균용 조성물(기술이전 완료)등록번호 : 10-2051549, 등록일자 : 2019-11-27
생물공학연구자상, 2020년 10월 22일, 한국생물공학회장
최우수논문 연구자상, 2017년 12월 29일, 순천대학교 총장
공로상, 2015년 10월 13일, 한국생물공학회장
우수강의상, 2011년 2월 10일, 순천대학교 총장
2011.05 ~ 2014.04, 교육부- 해양자원으로부터 얻은 키토산을 이용한 다기능성 생체의료용 장치의 제조
2015.08 ~ 2017.07, 산업통상자원부- 이소소르비드 기반 살균, 소독 기능의 친환경, 고효율 계면활성제 개발
2015.05 ~ 2016.04, 중소기업벤처부- 발효산업용 자기유화형 고효율, 무독성 소포제의 개발
2017.03 ~ 2020.02, 과학기술정보통신부-4차원 나노구조 케이지단백질, 생체고분자, 펩타이드를 이용한 생체친화형 약물전달체 개발
2020.03 ~ 2023.02, 과학기술정보통신부- 암줄기세포 표적 치료 및 면역세포 활성화를 위한 엑소좀 기반 약물전달 시스템 개발
Lee, J., Lee, W., Ryu, K. H., Park, J., Lee, H. J., Lee, J. H., & Park, K. T. (2021). Catholyte-free electroreduction of CO 2 for sustainable production of CO: Concept, process development, techno-economic analysis, and CO 2 reduction assessment. Green Chemistry.
Ryu, K. H., Kim, B., Kim, H. S., Chang, Y. K., & Lee, J. H. (2020) A mathematical modeling of microalgal internal metabolic behaviors under heterotrophic condition and its application. Industrial & Engineering Chemistry Research, 59, 1631-1645.
Lee, J., Ryu, K. H., Jung, K., Ha, H. Y., & Lee, J. H. (2020) Techno-economic and environmental evaluation of mineral carbonation process utilizing the steel slag. Journal of CO2 utilization, 37, 113-121.
Ryu, K. H., Lee, J. Y., Heo, S. M., & Lee, J. H. (2019). Improved microalgae production by using a heat supplied open raceway pond. Industrial & Engineering Chemistry Research, 58, 9099-9108.
Ryu, K. H., Kim, B., & Lee, J. H. (2019). A model-based optimization of microalgal cultivation strategies for lipid production under photoautotrophic condition. Computers & Chemical Engineering, 121, 57-66.
Ryu, K. H., Sung, M. G., Kim, B., Heo, S., Chang, Y. K., & Lee, J. H. (2018). A mathematical model of intracellular behavior of microalgae for predicting growth and intracellular components syntheses under nutrient replete and deplete conditions. Biotechnology and bioengineering, 155(10), 2441-2455. (Cover paper)
Kwon, W. H., Ryu, K. H., Hwang, J. A., Kim, K. H., Lee, J. H., & Sung, S. W. (2018). Development of batch proportional-integral-derivative controller. Korean Journal of Chemical Engineering, 35(6), 1-7.
Yun, C. Y., Ryu, K. H., Lee, C., Lee, G. G., Jo, S., Kim, K. H., & Sung, S. W. (2017). Modeling and Simulation of Solvent Extraction Processes for Purifying Rare Earth Metals Using Saponified PC88A. Journal of Chemical Engineering of Japan, 50(9), 716-726.
Ryu, K. H., Lee, S. N., Nam, C. M., Lee, J., & Sung, S. W. (2014). Discrete-time frequency response identification method for processes with final cyclic-steady-state. Journal of Process Control, 24(6), 1002-1014.
Jin, C. Y., Ryu, K. H., Sung, S. W., Lee, J., & Lee, I. B. (2014). PID auto-tuning using new model reduction method and explicit PID tuning rule for a fractional order plus time delay model. Journal of Process Control, 24(1), 113-128.
Ryu, K. H., Lee, C., Lee, G. G., Jo, S., & Sung, S. W. (2013). Modeling and simulation of solvent extraction processes for purifying rare earth metals with PC88A. Korean Journal of Chemical Engineering, 30(10), 1946-1953.
2021.01 ~2021.12, 한국연구재단- Simulation and evaluation of 10MW oxy-CFBC on the diversification of fuel
2020.09 ~ 2020.12, 한국에너지연구원- USC steam cycle optimization by using ASPEN PLUS
2020.04 ~ 2020.07, 한국연구재단- Development of the high-efficiency low-emission future energy production technology
2019.02 ~ 2019.09, POSCO- Development of CO2 pathway analysis method for steel manufacturing process
2019.02 ~ 2020.01, 한국연구재단- Technical economic analysis and emission of CO2 reduction analysis for novel capture, conversion, and storage processing pathways by modeling and simulation
2017.05 ~ 2018.02, 미래창조과학부- Design and economic analysis of overall process through systematic simulation”
Young Jae Choi*, Jong Uk Lee*, Sang Jun Sim, Nanoplamonic biosensing of specific LC3 autophagy markers enabling drug discovery of autophagy modulators, Sensors and Actuators: B. Chemical, 363,131744 (2022), 3.91%, IF=7.460 (*co-first author)
Woo Hyun Kim*, Jong Uk Lee*, Myeong Jin Jeon, Kyong Hwa Park, Sang Jun Sim, Three-dimensional hierarchical plasmonic nano-architecture based label-free surface-enhanced Raman spectroscopy detection of urinary exosomal miRNA for clinical diagnosis of prostate cancer, Biosensor and Bioelectronics, 205, 114116 (2022), IF=10.618 (*co-first author)
Su Ji Yang*, Jong Uk Lee*, Myeong Jin Jeon, Sang Jun Sim, Highly sensitive surface-enhanced Raman scattering-based immunosensor incorporating half antibody-fragment for quantitative detection of Alzheimer's disease biomarker in blood, Analytica Chimica Acta, 1195, 339445 (2022), IF=6.558 (*co-first author)
Sojin Song*, Jong Uk Lee*, Myeong Jin Jeon, Soohyun Kim, Sang Jun Sim, Detection of multiplex exosomal miRNAs for clinically accurate diagnosis of Alzheimer's disease using label-free plasmonic biosensor based on DNA-Assembled advanced plasmonic architecture, Biosensor and Bioelectronics, 119, 113864 (2022), IF=10.618 (*co-first author)
Young jae Choi*, Jong Uk Lee*, Sang Jun Sim, Label-free and highly sensitive nanoplasmonic biosensor-based autophagy flux sensing for clinical application, Sensors and Actuators B: Chemical, 350, 130880 (2022), IF=7.46 (*co-first author)
Myeong Jin Jeon*, Xingyi Ma*, Jong Uk Lee, Hyejin Roh, Conrad C. Bagot, Wounjhang Park, Sang Jun Sim, Precisely Controlled Three-Dimensional Gold Nanoparticle Assembly Based on Spherical Bacteriophage Scaffold for Molecular Sensing via Surface-Enhanced Raman Scattering, The Journal of Physical Chemistry C, 125, 2502-2510 (2021), IF=4.189 (*co-first author)
Sojin Song, Jong Uk Lee, Jinho Kang, Kyung Hwa Park, Sang Jun Sim, Real-time monitoring of distinct binding kinetics of hot-spot mutant p53 protein in human cancer cells using an individual nanorod-based plasmonic biosensor, Sensors and Actuators B: Chemical, 322, 128584 (2020), Cited by 1, IF=7.100
Jong Uk Lee*, Soohyun Kim*, Sang Jun Sim, SERS-based Nanoplasmonic Exosome Analysis: Enabling Liquid Biopsy for Cancer Diagnosis and Monitoring Progression, BioChip Journal, 14, 231-241 (2020), IF=2.309 (*co-first author)
Jong Uk Lee*, Woo Hyun Kim*, Hye Sun Lee, Kyong Hwa Park, Sang Jun Sim, Quantitative and Specific Detection of Exosomal miRNAs for Accurate Diagnosis of Breast Cancer Using a Surface-Enhanced Raman Scattering Sensor Based on Plasmonic Head-Flocked Gold Nanopillars, Small, 15(17), 1804968 (2019), Cited by 34, IF=11.459 [Selected as Back Cover] (*co-first author)
Hanbi Kim*, Jong Uk Lee*, Soohyun Kim, Sojin Song, Sang Jun Sim, A Nanoplasmonic Biosensor for Ultrasensitive Detection of Alzhimer's Disease Biomarker Using a Chaotropic Agent, ACS Sensors, 4(3), 595-602 (2019), Cited by 13, IF=7.333 (*co-first author)
Woo Hyun Kim*, Jong Uk Lee*, Sojin Song, Soohyun Kim, Young Jae Choi, Sang Jun Sim, Label-free, ultra-highly sensitive and multiplexed SERS nanoplasmonic biosensor for miRNA detection using head-flocked gold nanopillar, Analyst, 144(5), 1768-1776 (2019), Cited by 15, IF=3.978 (*co-first author)
Hanbi Kim, Jong Uk Lee, Sojin Song, Soohyun Kim, Sang Jun Sim, A shape-code nanoplasmonic biosensor for multiplex detection of Alzheimer's disease biomarkers, Biosensors and Bioelectronics, 101, 96-102 (2018), Cited by 33, IF=10.257
Dominique Ingato, Jong Uk Lee, Sang Jun Sim, Young Jik Kwon, Good things come in small packages: Overcoming challenges to harness extracellular vesicles for therapeutic delivery, Journal of Controlled Release, 4(4), 240-248 (2016), Cited by 69, IF=7.727
Sojin Song, Anh H. Nguyen, Jong Uk Lee, Misun Cha, Sang Jun Sim, Tracking of STAT3 signaling for anticancer drug-discovery based on localized surface plasmon resonance, Analyst, 141(8), 2493-2501 (2016), Cited by 4, IF=3.978
Anh H. Nguyen, Jong Uk Lee, Sang Jun Sim, Nanoplasmonic probes of RNA folding and assembly during pre-mRNA splicing, Nanoscale, 8(8), 4599-4607 (2016), Cited by 4, IF=6.895
Jong Uk Lee, Anh H. Nguyen, Sang Jun Sim, A nanoplasmonic biosensor for label-free multiplex detection of cancer biomarkers, Biosensors and Bioelectronics, 74, 341-346 (2015), Cited by 52, IF=10.257
Anh H. Nguyen, Jong Uk Lee, Sang Jun Sim, Plasmonic coupling-dependent SERS of gold nanoparticles anchored on methylated DNA and the detection of global DNA methylation using SERS-based platforms, Journal of Optics, 17(11), 114022 (2015), Cited by 5, IF=2.379
Jong Uk Lee, Ji Hoon Jeong, Doo Sung Lee, Sang Jun Sim, Signal enhancement strategy for a micro-arrayed polydiacetylene (PDA) immunosensor using enzyme-catalyzed precipitation, Biosensors and Bioelectronics, 61, 314-320 (2014), Cited by 18, IF=10.257
Sang Ho Won, Jong Uk Lee, Sang Jun Sim, Fluorogenic pH-sensitive polydiacetylene (PDA) liposomes as a drug carrier, Journal of Nanoscience and Nanotechnology, 13(6), 3792-3800 (2013), Cited by 10, IF=1.134
2020.07 - PresentNanophotonics-based Biomedical Diagnostics Research Center (National Research Foundation of Korea, Engineering Research Center Program)
2020.04 - PresentDevelopment of novel optics-based immunodiagnostic technology for efficient diagnosis of COVID-19 (Kyungnam Pharm Co. Ltd.)
2019.03 - PresentThe development of bio-platform for liquid biopsy of incurable disease by optical instrument based on biomaterial-directed asymmetric nanoparticle (National Research Foundation of Korea, Mid-career Research Supporting Program)
2017.12 - 2019.04Development of hybrid simultaneous treatment process using carbon capture and utilization system for CO2 from flue gas (Korea Institute of Energy Technology Evaluation and Planning, Energy Technology Development Program)